diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index 94e9fd30a79..955dacfbb89 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -10145,6 +10145,11 @@ namespace ts {
             if (objectType === wildcardType || indexType === wildcardType) {
                 return wildcardType;
             }
+            // If the object type has a string index signature and no other members we know that the result will
+            // always be the type of that index signature and we can simplify accordingly.
+            if (isStringIndexSignatureOnlyType(objectType) && !(indexType.flags & TypeFlags.Nullable) && isTypeAssignableToKind(indexType, TypeFlags.String | TypeFlags.Number)) {
+                indexType = stringType;
+            }
             // If the index type is generic, or if the object type is generic and doesn't originate in an expression,
             // we are performing a higher-order index access where we cannot meaningfully access the properties of the
             // object type. Note that for a generic T and a non-generic K, we eagerly resolve T[K] if it originates in
@@ -12022,6 +12027,12 @@ namespace ts {
             return !!(getObjectFlags(type) & ObjectFlags.Anonymous) && isEmptyObjectType(type);
         }
 
+        function isStringIndexSignatureOnlyType(type: Type): boolean {
+            return type.flags & TypeFlags.Object && getPropertiesOfType(type).length === 0 && getIndexInfoOfType(type, IndexKind.String) && !getIndexInfoOfType(type, IndexKind.Number) ||
+                type.flags & TypeFlags.UnionOrIntersection && every((<UnionOrIntersectionType>type).types, isStringIndexSignatureOnlyType) ||
+                false;
+        }
+
         function isEnumTypeRelatedTo(sourceSymbol: Symbol, targetSymbol: Symbol, errorReporter?: ErrorReporter) {
             if (sourceSymbol === targetSymbol) {
                 return true;