diff --git a/src/services/inlayHints.ts b/src/services/inlayHints.ts
index ce779052a05..a3e54cf2378 100644
--- a/src/services/inlayHints.ts
+++ b/src/services/inlayHints.ts
@@ -119,6 +119,7 @@ import {
     TupleTypeReference,
     Type,
     TypeFlags,
+    TypePredicate,
     unescapeLeadingUnderscores,
     UserPreferences,
     usingSingleLineStringWriter,
@@ -405,6 +406,16 @@ export function provideInlayHints(context: InlayHintsContext): InlayHint[] {
             return;
         }
 
+        const typePredicate = checker.getTypePredicateOfSignature(signature);
+
+        if (typePredicate?.type) {
+            const hintParts = typePredicateToInlayHintParts(typePredicate);
+            if (hintParts) {
+                addTypeHints(hintParts, getTypeAnnotationPosition(decl));
+                return;
+            }
+        }
+
         const returnType = checker.getReturnTypeOfSignature(signature);
         if (isModuleReferenceType(returnType)) {
             return;
@@ -474,6 +485,17 @@ export function provideInlayHints(context: InlayHintsContext): InlayHint[] {
         });
     }
 
+    function printTypePredicateInSingleLine(typePredicate: TypePredicate) {
+        const flags = NodeBuilderFlags.IgnoreErrors | NodeBuilderFlags.AllowUniqueESSymbolType | NodeBuilderFlags.UseAliasDefinedOutsideCurrentScope;
+        const printer = createPrinterWithRemoveComments();
+
+        return usingSingleLineStringWriter(writer => {
+            const typePredicateNode = checker.typePredicateToTypePredicateNode(typePredicate, /*enclosingDeclaration*/ undefined, flags);
+            Debug.assertIsDefined(typePredicateNode, "should always get typePredicateNode");
+            printer.writeNode(EmitHint.Unspecified, typePredicateNode, /*sourceFile*/ file, writer);
+        });
+    }
+
     function typeToInlayHintParts(type: Type): InlayHintDisplayPart[] | string {
         if (!shouldUseInteractiveInlayHints(preferences)) {
             return printTypeInSingleLine(type);
@@ -481,10 +503,24 @@ export function provideInlayHints(context: InlayHintsContext): InlayHint[] {
 
         const flags = NodeBuilderFlags.IgnoreErrors | NodeBuilderFlags.AllowUniqueESSymbolType | NodeBuilderFlags.UseAliasDefinedOutsideCurrentScope;
         const typeNode = checker.typeToTypeNode(type, /*enclosingDeclaration*/ undefined, flags);
-        Debug.assertIsDefined(typeNode, "should always get typenode");
+        Debug.assertIsDefined(typeNode, "should always get typeNode");
+        return getInlayHintDisplayParts(typeNode);
+    }
 
+    function typePredicateToInlayHintParts(typePredicate: TypePredicate): InlayHintDisplayPart[] | string {
+        if (!shouldUseInteractiveInlayHints(preferences)) {
+            return printTypePredicateInSingleLine(typePredicate);
+        }
+
+        const flags = NodeBuilderFlags.IgnoreErrors | NodeBuilderFlags.AllowUniqueESSymbolType | NodeBuilderFlags.UseAliasDefinedOutsideCurrentScope;
+        const typeNode = checker.typePredicateToTypePredicateNode(typePredicate, /*enclosingDeclaration*/ undefined, flags);
+        Debug.assertIsDefined(typeNode, "should always get typenode");
+        return getInlayHintDisplayParts(typeNode);
+    }
+
+    function getInlayHintDisplayParts(node: Node) {
         const parts: InlayHintDisplayPart[] = [];
-        visitForDisplayParts(typeNode);
+        visitForDisplayParts(node);
         return parts;
 
         function visitForDisplayParts(node: Node) {
diff --git a/tests/baselines/reference/inlayHintsInferredTypePredicate1.baseline b/tests/baselines/reference/inlayHintsInferredTypePredicate1.baseline
new file mode 100644
index 00000000000..df607df5111
--- /dev/null
+++ b/tests/baselines/reference/inlayHintsInferredTypePredicate1.baseline
@@ -0,0 +1,9 @@
+// === Inlay Hints ===
+function test(x: unknown) {
+                         ^
+{
+  "text": ": x is number",
+  "position": 25,
+  "kind": "Type",
+  "whitespaceBefore": true
+}
\ No newline at end of file
diff --git a/tests/baselines/reference/inlayHintsInteractiveInferredTypePredicate1.baseline b/tests/baselines/reference/inlayHintsInteractiveInferredTypePredicate1.baseline
new file mode 100644
index 00000000000..7bc4345bf09
--- /dev/null
+++ b/tests/baselines/reference/inlayHintsInteractiveInferredTypePredicate1.baseline
@@ -0,0 +1,23 @@
+// === Inlay Hints ===
+function test(x: unknown) {
+                         ^
+{
+  "text": "",
+  "displayParts": [
+    {
+      "text": ": "
+    },
+    {
+      "text": "x"
+    },
+    {
+      "text": " is "
+    },
+    {
+      "text": "number"
+    }
+  ],
+  "position": 25,
+  "kind": "Type",
+  "whitespaceBefore": true
+}
\ No newline at end of file
diff --git a/tests/cases/fourslash/inlayHintsInferredTypePredicate1.ts b/tests/cases/fourslash/inlayHintsInferredTypePredicate1.ts
new file mode 100644
index 00000000000..fd1de15cd9f
--- /dev/null
+++ b/tests/cases/fourslash/inlayHintsInferredTypePredicate1.ts
@@ -0,0 +1,11 @@
+/// <reference path="fourslash.ts" />
+
+// @strict: true
+
+//// function test(x: unknown) {
+////   return typeof x === 'number';
+//// }
+
+verify.baselineInlayHints(undefined, {
+  includeInlayFunctionLikeReturnTypeHints: true,
+});
diff --git a/tests/cases/fourslash/inlayHintsInteractiveInferredTypePredicate1.ts b/tests/cases/fourslash/inlayHintsInteractiveInferredTypePredicate1.ts
new file mode 100644
index 00000000000..88282cf849e
--- /dev/null
+++ b/tests/cases/fourslash/inlayHintsInteractiveInferredTypePredicate1.ts
@@ -0,0 +1,12 @@
+/// <reference path="fourslash.ts" />
+
+// @strict: true
+
+//// function test(x: unknown) {
+////   return typeof x === 'number';
+//// }
+
+verify.baselineInlayHints(undefined, {
+  interactiveInlayHints: true,
+  includeInlayFunctionLikeReturnTypeHints: true,
+});
\ No newline at end of file